Research Update

[vc_row][vc_column][vc_column_text]Keratoconus research is moving forward on many fronts. Laboratory scientists are searching for the elusive cause (or causes) of keratoconus by examining the ways in which the KC cornea differs from the normal cornea and clinical scientists are looking for better treatment options to improve the quality of life for those with KC.

Second Generation CXL Treatment

Currently in animal studies, a second generation crosslinking method is being developed that may expand the range of patients that can be treated.. Consequently, CXL is unavailable to the many patients with thinned corneas.

For safety reasons, current CXL protocols cannot be used to crosslink thin corneas, defined as those less than about 400 µm (1/60th of an inch) thick. This is a problem because during progression of keratoconus, the cornea becomes thinner as the cornea stretches forward. Recently, a novel crosslinking method (currently in animal studies) was reported that might overcome this barrier to treatment of thin corneas. Read more…


Custom Contact Lenses Using Wavefront Sensing

Why is it that glasses don’t always work for patients with keratoconus? In many instances, individuals with keratoconus do not achieve excellent visual performance with spectacles or traditional soft contact lenses. One cause for the failure of these corrections is that the changes in corneal shape that accompany keratoconus induce refractive errors which traditional spectacles simply cannot correct. So, even when sphere and cylinder in the keratoconic eye are well-corrected, these “other refractive errors” or “other aberrations” remain uncorrected and can lead to a blurred retinal image and blurred vision. Collectively these other aberrations can be referred to as higher order aberration, while the aberrations that are typically corrected with spectacles and soft contact lenses are referred to as lower order aberration. Read more…