US CXL Sites

Corneal Crosslinking Sites in the US

Corneal Crosslinking (CXL), a procedure first developed in Dresden, Germany in the 1990’s, has the potential to stop the progression of Keratoconus. This is a treatment option under investigation for individuals with progressive keratoconus to stabilize the cornea.
Corneal Crosslinking (CXL) has been used in Europe and other countries for several years and is currently undergoing FDA clinical trials in the United States.

While data from these initial clinical trials is being collected for review by the FDA, a number of sites in the United States are offering corneal crosslinking under investigator sponsored clinical studies. These sites are using protocols approved by various Institutional Review Boards.

All the following studies are listed on the National Institute for Health (NIH) website: or have IRB approval.

(An Institutional Review Board (IRB) is a committee formally designated to approve, monitor and review research involving human subjects to protect the rights and welfare of the research subjects. The Food and Drug Administration (FDA) and the Office of Protection from Research Risks (part of the National Institutes of Health) set the guidelines and regulations governing human subjects research and IRBs.)

Note: Cost for this procedure varies. Call the offices for specific information.


Identifier: NCT01189864
Principal Investigator: Jay L. Schwartz, MD
Schwartz Laser Eye Center
8416 E. Shea Blvd Ste C-101
Scottsdale, AZ 85260
Contact: 480-483-3937

Identifier # NCT01190306
Principal Investigator: Robert Rivera, M.D.

Barnet Dulaney Perkins Eye Center
4800 North 22nd Street
Phoenix, AZ 85016
Contact Person:Patti Crincoli
Contact phone # 602-508-4871

Identifier: NCT01398852 (Topcon)
Principal Investigator: Scott Perkins, M.D.
Barnet Dulaney Perkins Eye Center
4800 North 22nd Street
Phoenix, AZ 85016


Identifier: NCT01081561
Principal Investigator: Yaron Rabinowitz, MD & Yuri Oleynikov, MD,PhD
Eye Surgery Center of Beverly Hills
Cornea Eye Institute
50 N. La Cienega Blvd. Ste. 340
Beverly Hills, CA 90211

Contact: Betty Cardenas (310) 423-9640
Contact: Martha Bucaram (310) 423-9640

Identifier: NCT01081561
Principal Investigator: Ezra Maguen, MD 

American Eye Institute
8635 West 3rd Street
Los Angeles, CA 90048-6150
Contact: Bernie Ruane (310) 652-1133

Identifier: NCT01081561
Principal Investigator: James Salz, MD 

Laser Eye Associates
240 So. La Cienega Blvd., Suite 250
Beverly Hills, CA 90211
Contact: Donna Jones (310) 360-0609

Identifier: NCT01081561
Principal Investigator: Ronald N. Gaster, MD, FACS 

Eye Surgery Center of Beverly Hills
Cornea Eye Institute
50 N. La Cienega Blvd. Ste. 340
Beverly Hills, CA 90211
Contact: toll free: 855-EYEDOC1 (855 393-3621)

Identifier: NCT01097447
Principal Investigator: David A. Wallace, MD 

LA Sight
11600 Wilshire Blvd. Suite 200
Los Angeles CA 90025
Contact: Karen Mrosko (310) 828-2020/ (877) 828-2020

Identifier: NCT01097447
Principal Investigator: Sandy Feldman, MD
Clear View Eye & Laser Medical Center
6255 Lusk Blvd., Suite 100
San Diego, CA 92121
Contact : 858- 452-3937

Identifier: NCT01097447
Principal Investigator: Dan Goodman, MD

Goodman Eye Center
2211 Bush St., 2nd floor
San Francisco, CA 94115
Contact: (415) 474-3333


Identifier: NCT01097447
Principal Investigator: Lance Forstot, MD
Sub-Investigator: Erik Letko, MD
Corneal Consultants of Colorado
8381 Southpark Lane
Littleton, CO 80120
Contact: Steven Cho (303) 730-0404


Identifier: NCT01024322
Principal Investigator: William Trattler, MD 

Center for Excellence in Eye Care
8940 N. Kendall Drive; #400E
Miami, FL 33176
Contact: Dr. Trattler: (305) 598-2020


Identifier: NCT00567671
Principal Investigator: Doyle Stulting, MD

Woolfson Eye Institute (previously at Emory University)
800 Mt. Vernon Hwy, Suite 120
Atlanta, GA 30328
Contact: Dr. Stulting (770) 255-3330

Identifier: NCT01190306
Principal Investigator: R. Doyle Stulting, MD, PhD

Woolfson Eye Institute
800 Mt. Vernon Hwy, Suite 120
Atlanta, GA 30328
Contact: Jodi Miller 770- 255-3330


Identifier: NCT01097447
Investigator: Parag A. Majmudar, MD
Chicago Cornea Consultants, Ltd.
1585 N. Barrington Road, Suite 502
Hoffman Estates, IL 60169
Contact : Jim Nykaza (847) 882-5900

Identifier: NCT01325298
Investigator: Robert L Epstein, M.D.
Mercy Center for Corrective Eye Surgery
5400 West Elm Street (Route 120) Suite 120
McHenry, IL 60050
Contact: Mark Gurgos, COT 815-363-2020


Identifier: NCT01143389
Principal Investigator: Francis Price, MD

Price Vision Group
9002 N. Meridian St. Ste.100
Indianapolis, IN 46260
Contact: Marianne Price, PhD 317-844-5530


Identifier: NCT00841386
Principal Investigator: Kathryn Colby, MD, PhD
Co-Investigator: Roberto Pineda II, MD
Massachusetts Eye and Ear Infirmary
243 Charles Street
Boston, MA 02114
Contact: Cornea Research Dept: (617) 573-3313


Identifier: NCT01024322
Principal Investigator: Roy Rubinfeld, MD
Washington Eye Center
5454 Wisconsin Ave, Suite 950
Chevy Chase, MD 20815
Contact: Roy Rubinfeld, MD (301) 654-5114

Identifier: NCT01190306 / NCT01398852 (Topcon)
Principal Investigator: David Hardten, MD
Minnesota Eye Consultants
Bloomington, Minnesota, 55431
Contact: Lindsey Fallenstein 952-567-6060
Jill Spude 952-567-6070


Identifier: # NCT01152541
Principal Investigator: Peter Hersh, MD
Cornea and Laser Eye Institute
300 Frank W. Burr Blvd – Suite 71
Teaneck, New Jersey 07666
Contact: BethAnn Furlong-Hibbert (201) 883-0505


Identifier: NCT00841386
Principal Investigator: James J Reidy, MD
Co-Investigator: Thomas Elmer, MD
Ira G. Ross Eye Institute
1176 Main Street
Buffalo, NY 14209
Contact: Jeanne Stutz (716) 881-7920

Identifier: NCT00841386
Principal Investigator: Michael Endl, MD
Co-Investigator: Thomas R Elmer, MD
Fichte, Endl, & Elmer EyeCare
Creekside Center
2825 Niagara Falls Blvd., Suite 130
Amherst, NY 14228
Contact: Linda Grant (716) 564-2020

(CXL) IRB Approval #103706
Principal Investigator: Stephen Trokel, MD
Columbia University / Harkness Eye Institute
635 West 165th Street
New York, NY 10032
Contact: David Mun (212) 305-5922

Identifier: NCT01189864
Principal Investigator: Jodi Luchs, MD
South Shore Eye Care
2185 Wantagh Ave
Wantagh, NY 11793
Contact: Dr. Luchs 516-785-3900

Identifier: NCT01398852 (Topcon)
Principle Investigator: Mark Speaker, MD
Laser and Corneal Surgery Associates, PC
115 East 57th Street, 16th Fl
New York NY, 10022
Contact: Christina Lanza 212-832-2020

Identifier: NCT01190306 / NCT01398852 (Topcon)
Principal Investigator: Gregory Pamel, MD 

Pamel Vision & Laser Group
New York, NY 10021
Contact: D. Sawhney, O.D. 212-355-2215

Identifier: NCT01398852 (Topcon)
Principal Investigator: Robert Schultze, MD
Cornea Consultants of Albany
Slingerland, NY 12159
Contact: Kamil San 518-475-1515


Identifier: NCT01189864
Principal Investigator: Shamik Bafna, MD
Cleveland Eye Clinic
7001 S. Edgerton Rd. Suite B
Breckville, OH 44141
Contact: 440-526-1974

Identifier: NCT01190306
Principal Investigators: Ron Krueger, MD & William Dupps, MD, PhD
Cleveland Clinic – Cole Eye Institute
Cleveland, OH 44195
Contact: Fadiah Alkhawaldeh 216-445-3641

Identifier: NCT01190306
Principal Investigator: Thomas Mauger, MD
OSU Department of Ophthalmology
Columbus, OH 43212
Contact: Barbara Landolfi 614-293-8760

Identifier: NCT01190306
Principal Investigator: George Waring IV, M.D.
Address: ReVision Advanced Laser Eye Center
1080 Polaris Pkwy #100
Columbus, Oh 43215
Contact phone # 614-781-0499


Identifier: NCT01097447
Principal Investigator: Bradley Bowman, MD
Cornea Associates of Texas
7150 Greenville, Ste. 600
Dallas, TX 75231
Contact: 214-692-0146

Identifier: NCT01190306 and  NCT01398852 (Topcon)
Principal Investigator: Stephen Slade, MD
Slade & Baker Vision Center
3900 Essex Ln. Suite 101
Houston, TX 77027
Contact: Leticia Fernandez 713-626-5544

Identifier # NCT01190306 and NCT01398852 (Topcon)
Principal Investigator: Steven Dell, M.D.
Address: Dell Laser Consultants
901 Mopac Expressway South, Suite 350
Barton Oaks Plaza IV
Austin, TX 78746
Contact Person: Allison Knox 512-347-0255


Identifier:  NCT01398852 (Topcon)
Principle Investigator: Darcy Wolsey, M.D.
The Eye Institute of Utah
755 East 3900 South
Salt lake City, UT 84107
(801) 266-2283

NKCF advises caution to patients who may be considering non approved clinical trials.